However, there were so many methodological issues I would not put any weight in these conclusions. Conclusion:On the surface it seems Ivermectin with doxycycline reduced the time to recovery, percentage of patients who progress to more advanced stages of disease and reduced mortality.No information on patients to see if groups were balanced (i.e.No idea if it’s the ivermectin or the doxycycline making the difference if you believe the difference.No clear definition of recovery making this a subjective outcome that can bias the study.Non-blinded: Everyone knew what they were taking.Unclear what earlier means as there were no critical patients in the SOC arm.Convenience sample: We have no idea how many patients total could have gotten treatment.This can have a tremendous effect on lowering the burden of disease and quickly freeing up hospital beds to other patients. In severe patients this reduction was from 24d to 20d.In mild to moderate patients this reduction was from 13.66d to 6.34d.Ivermectin-Doxycycline reduced mean time to recovery from 17.9 to 10.61d in all recruited patients.Randomized controlled trial of 140 patients:.There’s simply too much unknown information to make anything of this paper other than a hypothesis to study. However, we don’t know the rates of COVID-19 in these countries, crowding, testing availability, etc. Conclusion:There seems to be an association rather than a causation of ivermectin use reducing COVID-19 incidence.The fact that prophylaxis without ivermectin also showed a strong and statistically significant association with COVID-19 incidence suggests that other drugs could include additional candidates for the treatment and/or prevention of COVID-19.Compared COVID-19 incidence between these three groups:.Do not include ivermectin in prophylaxis.Grouped countries into three different categories:.Observational Data from Countries Using Prophylactic Ivermectin vs Those not Using Prophylactic Ivermectin
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |